Extra pounds are the cause of many metabolic disorders, including increasing the risk of developing diabetes type 2 and cardiovascular diseases. It is logical to assume that the decrease in body weight may be accompanied by a decrease in the risk of metabolic disorders in people with obesity. Dr. Hives Johnson and his team have identified how these risks depend from the dropped pounds in obese patients.
The authors analyzed a two-year randomized study that included the 390 people with obesity and concluded that patients with a high degree of obesity can significantly improve your metabolic risks associated with weight loss of more than 5 percent.
All patients in the study took part in an active program to reduce weight, which consisted of several phases.
The first phase lasted 12 weeks and included a low-calorie diet with the addition of 10 g fat (fish oil or 2 teaspoons vegetable oil).
The second phase lasted 4 months and included a well-balanced diet, medication (sibutramin) and changing nutritional behavior (studies on correction were performed weekly during the first month and then twice a week for three months).
In the third phase, medicamental correction was not required and was only in the group with low response to earlier treatment.
Medical monitoring was carried out on a monthly basis for each patient. The average weight loss was 13.1 percent in the intensive group.
Weight loss was significantly correlated with indicators of the level of glucose in blood plasma, triglycerides, high and low density lipoprotein cholesterol, uric acid, alanine aminotransferase, lactate dehydrogenase and high-sensitivity C-reactive protein. Most of the settings gradually improved with 5% or more loss of body weight. In addition to low-density lipoprotein cholesterol, they have improved significantly from a loss of body weight more than 20%.
The problems associated with excess body weight are a serious threat to national health. This study shows that the normalization of body weight has a positive effect on health by eliminating the risk factors for cardiovascular and metabolic diseases.
Source: the American journal of medicine, October 2011