Topiramate is used to treat epilepsy for a long time. Scientists from the University of Pennsylvania found that the agent is effective for treatment of alcoholism. Scientists investigated the safety of topiramate and its effectiveness in this disease.
The study included 138 volunteers, who were divided into two groups. The first group received the drug at a dosage of 200 mg for 12 weeks. The second group received placebo. In addition, all volunteers were talking and advice on how to quit drinking.
The results have surprised scientists. When taking topiramate craving for alcohol has decreased five times. Patients significantly reduced the amount of alcohol consumed. In blood decreased number gamma-glutamyltranspeptidase. This substance causes cirrhosis of the liver.
Previously, scientists have proven the effectiveness of the tool in relation to the treatment of cocaine addiction. Topiramate kept addicts from abusing substances.