Milk fat is a stimulant of bile secretion, which is a favorable environment for the growth of bacteria that cause intestinal inflammatory diseases.
Intestinal inflammation is traditionally associated with violations of the agreement on non-aggression between bacterial symbionts of the intestine and immune system. The immune system observes that the microorganisms observed decency" and not even thought about the introduction into the tissues of the intestine: the work of its bacteria perform well, but only if environmental limits. Violators of the just destroys the immune system, preventing the full development of the disease. Because the cause of various intestinal inflammation can see there is a malfunction of the immune system. Normal bacteria symbionts, begin to actively harm in gaining access to the tissues of the host body.
But the flaws in the immune protection of the risk of disease are increasing, and the one here is not enough, you want something else, writes the online edition of componenta. Experts from the University of Chicago (USA) believe that the direct cause of the disease is likely milk fat in the food industry is very popular: it generously add in groceries and confectionery.
Scientists have used the mouse, which was off the gene interleukin-10 (immune proteins), it is necessary to keep the intestinal microflora. If the mice keep on a low-fat diet or in their diet were added polyunsaturated fatty acids, i.e. the probability that the intestinal colitis will develop in 20% of cases. If food add milk fat, in this case, the frequency of inflammation of the intestine will increase threefold, and the symptoms will be much heavier than those animals that "keep" a low-fat diet.
In an article published in the journal Nature, the authors of this "work" of milk fat is associated with the bacterium Bilophila wadsworthia. This type of bacteria is present in the normal intestinal flora, but in very small quantities. However, in the presence of saturated milk fat, its share increased to 6 percent. Fats become a cause of increased bile flow, which in turn helps them to break down and creates favorable conditions for the growth of B. wadsworthia. The metabolic products of the above bacteria increase for antibacterial barrier permeability, and in this case, the microflora can reach the intestinal wall.
About the negative effects of B. wadsworthia scientists have long known: its vigorous reproduction followed by appendicitis and other gastrointestinal inflammatory troubles. Here it is very important that a regular production of milk fat may, in the truest sense of the word to start the disease, if the person has a genetic predisposition.
Scientists believe that the increased frequency of these diseases directly associated with the peculiarities of human nutrition, and food production: themselves immune defects are not so terrible, but only if they do not give rise to manifest.