According to scientists, a substance called apigenin, naturally contained in parsley and celery, is a promising tool in the fight against breast cancer.
Researchers from the University of Missouri was found that apigenin has the unique ability to reduce the size of cancerous tumors, but only if tumor growth is stimulated by progestin - chemical special connection that it is recommended that women taking hormone replacement therapy to combat symptomatic manifestations of menopause.
Researchers from several mice was implanted kind of cancer cells BT-474, which traditionally lead to the rapid growth of the cancer and subsequent death. Subsequently, the experimental animals were obtained medroxyprogesterone acetate is a type of progestin that is just right during menopause and prescribed to women.
The animals of the test group also received and apigenin. This means the control group did not. Scientists in the result it was observed that the growth rate of the cancer in the control group was standard, while in the experimental group not only is it significantly slowed down, but almost 90 percent of cases was established regression of the disease. In other words, the tumor began to shrink in size, and simultaneously to decrease the affected area and, accordingly, the body damage and the possibility of metastasis virtually eliminated.
"We just can't know how apigenin it makes on a chemical level. But we were able to establish that apigenin have slowed down the progress of breast cancer cells in several ways: caused cell death, the method of inhibiting cell proliferation, and by reducing expression of a gene that is associated with the spread of cancer through the blood vessels. This is a very important point, because the nutrient flow to tumors was limited and probably led to the fact that cancer cells starved, and this fact has undermined the ability of the cancer to further spread," says Dr. salmon Haider (Salman Hyder, one of the authors of the study.
Researchers did not exclude that apigenin may also prove to be very useful as a prophylactic treatment of some types of cancer, but to confirm this hypothesis requires further research.