A research group from Thomas Jefferson University proved that overweight people 1.5 times more likely to suffer from kolorektalnah cancer than lean. The conclusion was made after the experiment with genetically modified mice. Animals received different food, tells The Times of India.
With the development of obesity in mice decreased the activity guanylin in the intestinal epithelium. This hormone is responsible for regeneration of the mucous membrane of the digestive tract. As a result, in the intestine there were multiple erosions, each of them potentially can develop into malignancy.
The researchers found the following: the drug works similarly Linaclotide guanidino. It activates the right receptors and reduces the risk of cancer in individuals with obesity. Doctors plan to conduct tests means to confirm or refute this information.