Oral contraceptives and increase the risk of stroke and heart attack

Danish researchers analyzed data on hormonal contraception over the past 15 years and concluded that its use can lead to stroke or myocardial infarction because of the increased risk of blood clots.

During the study analyzed medical data 1626158 women aged 15 to 49 years using hormonal contraceptives. In total the group has been 3311 Trombitsky stroke and 1725 heart attack.

The doctors were able to identify that the use of oral contraceptives for women, containing ethinylestradiol in an amount from 30 to 40 μg, led to increased probability of stroke or heart attack. Depending on the type of progestin, the risk was increased up to 2 times. For example, norethindrone increased the risk of stroke and heart attack by 2.2 and 2.3 times, respectively, 1.7 and 2 levonorgestrel, 1.6 and 1.7 - drospirenone, 1.8, and 1.9 - gestodene.

The dose of 20 mcg also increased risks: gestodene - 1.7 and 1.2, desogestrel - 1.5 and 1.6, drospirenone - 0.9 and 0.0.

It should be noted that the transdermal patches were among the most dangerous in terms of stroke, increasing its probability in 3, 2, but they do not affect the chance of getting a heart attack. Vaginal ring increases the risk of disease in average 2, 5.

Read also: Oral contraceptives lead to diseases of the gall bladder

Although the data was not frightening, doctors noted a comparative increase in risk of the disease with the use of contraceptives with certain type of progestin.

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