Results of two large clinical studies that have determined that long-term use of nonsteroidal anti-inflammatory drugs leads to decreased levels of hemoglobin, as a result of anemia.
Nonsteroidal anti-inflammatory drugs long-term use patients who suffer from chronic pain. It is sick with headaches, pain in joints and back. They have to take the drugs belonging to this group more than six months without interruption and in large enough doses.
Despite its anti-inflammatory and analgesic properties, these drugs have toxic effects on the hematopoietic system and cause a reduced level of hemoglobin, resulting in anemia and impaired trophic throughout the body.
The most common non-steroidal anti-inflammatory drugs include aspirin, diclofenac, celecoxib.
To date, no clear recommendations how to replace a long-term intake of this vital group of drugs for many patients. It is clear that reducing the dose and duration of intake may prevent the development of serious complications.