Cirrhosis is multifactorial progressive disease characterized by progressive fibrosis (replacement of organ tissues connective tissue), the reduction in the number of functioning of liver cells (hepatocytes), the restructuring of the authority and in the subsequent development of his failure, portal hypertension. Cirrhosis of the liver the liver cells die under the influence of various damaging factors, begins to develop fibrous tissue, forming the characteristic nodules and rebuilt the entire structure of the liver. As a result, the body is no longer able to perform its functions.
Annually from cirrhosis in the world kills more than 300 thousand people. The number of cases is rapidly increasing. In 12% of chronic alcoholics is asymptomatic during this insidious disease. According to statistics, cirrhosis more frequently diagnosed in men after 40 years.
Causes of cirrhosis of the liver:
• viral hepatitis (C, b, G, Delta);
• systemic abuse of alcohol;
• metabolic disorders;
• the body's response to drugs, toxic and chemical substances;
• receiving hepatotoxic drugs;
• biliary disease;
• venous congestion of the liver, which is delayed for a long time (when the constrictive pericarditis, venooclusive disease, heart failure).
For the disease characterized by a variety of manifestations. Typically, symptoms of cirrhosis of the liver depend on the stage of the disease and the reasons that caused it. At the initial stage of cirrhosis(class a) any complications are absent more often. If in this period, not to let it take its course and eliminate the cause of the disease, the healthy tissue of the organ will be saved and people will be able to lead a normal life.
If the patient increases the volume of the abdomen, changes behavior and consciousness, often bleeding gums, for unexplained reasons arise nosebleeds, then we can talk about complicated cirrhosis (classes b, C).
Patients with cirrhosis often complain of fatigue, and various disorders of behavior and consciousness (violation of nighttime sleep, daytime sleepiness, poor concentration etc), weight loss, abdominal discomfort (feeling of saturation, swelling), loss of appetite, jaundice (yellow colouring color of the sclera), bleaching or lightening of the stool, abdominal pain, dark urine, swelling of legs, enlarged abdomen due to the presence of abdominal free fluid, bleeding (nose, gums, hemorrhoid, gastrointestinal, subcutaneous), susceptibility to bacterial infections, decreased libido (in men) and gynecomastia (women). While the liver can both increase and decrease. However, in any case, this disease is characterized by the sealing body.
In humans, increased spleen may cause symptoms of jaundice, hypertension. Aching or dull pain in the liver increases after physical work or if the person made an error in diet. In body tissues accumulate bile acids, which leads to the occurrence of dyspeptic symptoms (diarrhea, vomiting, nausea), skin itching.
Cirrhosis is not an incurable fatal disease, as I think many who hear this diagnosis. To be treated and observed patients with cirrhosis should in specialized hospitals.
First of all, if possible, resolve the cause of the disease, then the doctor chooses the optimal treatment regimen for each individual patient. If medication is ineffective, the patient is included in the waiting list for those who need a liver transplant. Cirrhosis treatment can be successful only in case of strict compliance with the recommendations of the doctor.