British scientists have conducted studies and have found that some genetic diseases, affecting the structure of the receptor gamma-aminobutyric acid can lead to the development of alcoholism in mice. Findings were published in the journal Nature Communications.
The gene Gabrb1 is responsible for the development of alcohol dependence. The presence of this structure in mice led to the fact that the animals began to consume alcohol in large quantities. The data was confirmed after a series of experiments with mice have revealed a mutation in this gene. So, 85% of mice with abnormal gene Garbr1 preferred water with alcohol normal water. It should be noted that a conventional mouse is not tolerated alcohol and drank only water.
Scientists plan to conduct additional research in this area and to identify a similar pattern among men. The obtained results can be used in the development of new methods for the treatment of alcohol dependence.