To date, there are 22 genes that can cause the development of various forms of schizophrenia, 13 of which have become known only recently, after the study, reported in Nature Genetics.
Schizophrenia is called distraction, disruption of thought processes, perception of reality, which is caused by an abnormality in the brain. Often accompanied by visual and auditory hallucinations and manic delirium.
For this study Patrick Sullivan, University of North Carolina, together with colleagues analyzed the structure of the genome 5,000 people suffering from schizophrenia and the same number of genomes of healthy individuals. Was conducted as a re-analysis of worldwide research in the field of studying the genetic nature of schizophrenia, which covered 8 thousand patients and 12 of thousands of healthy people.
Eventually, scientists have found 22 stretch of DNA that are associated with the risk of developing schizophrenia. 13 of them were discovered for the first time and have not been previously known.
Analyzing the received information, scientists have put forward the theory that there is a relationship between disease and impaired signal transmission on calcium channels. These channels are present in all cells of the body, they are involved in muscle contraction, transmission of nerve impulse, the acquisition and assimilation of information. Disruption of calcium ions, may be associated with development of autism and schizophrenia with manic psychosis.
Today, schizophrenia is a fairly common disease. 24 million people worldwide are considered. Most often, the symptoms are found in age from 15 to 35 years, and the exact causes of schizophrenia scientists have not yet been established.