The majority of scientific studies before clinical trials are phase experiments on laboratory mice. The main reason is security and the relative cheapness of such studies, writes Science World Report. According to the latest data collected by scientists from Stanford University, studies in mice may not coincide with the results of experiments with volunteers from among the people.
The whole point of genetic differences. During analysis it was found that the human genome and the mouse have little in common. In some cases it is difficult to compare the results of clinical trials and laboratory research with animals.
Scientists have found about 4 thousands of genes shared by humans and mice, but the degree of their manifestation (expression) differed. A separate study of 15 genes showed that the degree of gene expression was similar in different tissues of the same species, but interspecific level of expression was very different.
However, the phenomenon may not work in all cases. Cardiac and hepatic tissue of human and mouse have a lot in common, in order to carry out the first stages of research on animals.