Living in the gastrointestinal tract billions of bacteria for human health are simply necessary. Special immune cells of these bacteria do not allow them to invade other tissues of the body. A group of researchers led by David Artis, representing the Medical school of the University of Pennsylvania (USA), demonstrated how this protection works, reported New Scientist.
As it turned out, the immune cells are innate lymphoid cells put some kind of barrier between the lining of the intestine and the neighboring tissues. If cells will not be able to contain the pressure of the bacteria, you will certainly begin the development of many diseases. For example, in the blood of patients suffering from Crohn's disease, there is increased to an abnormal level, the concentration of microbes.
Assistants for their work were forced to turn to animal models. When the scientists made the destruction of immune cells from mice, the mass of bacteria with ease began to penetrate in various organs. In normal mode cells functioned so they simply highlights the connection interleukin-22. Accordingly, the introduction of the above compounds were allowed to carry out compensation of the lack of protective mechanism.