Scientists from Japan believe, a separate group of people suffers from obesity because of the presence in the body of foci of chronic inflammation. The results of the work done and the conclusions tells the online edition of Science Advances.
In the experiment, scientists gave laboratory mice a chronic inflammation. Such conditions in most cases resulted in weight gain in rodents. It is possible that the extra weight comes from the disruption of TLR9 protein responsible for innate immunity.
Inflammation may disturb the resistance of tissues to insulin, and cause diabetes.
Scientists, suppressing the formation of the protein TLR9, was made to reduce the inflammation. As a result, the mouse became more sensitive to the action of insulin, adipose tissue was absorbed.
Not always obesity is due to overeating, summarize the researchers. In some cases excess weight may be associated with disorders of the endocrine system and other reasons.